I-4 E To Fl-33 N/Lakeland Hills Blvd. In Lakeland, Take Exit 33 From I-4 E, Merge Onto I-275 N, Use The Right Lanes To Take Exit 45 B For I-4 Toward Orlando, Continue Onto I-4 E, Take Exit 33 For Fl-33 Toward Lakeland, Take Old Combee Rd And Fl-659 S To State Hwy 546/Saddle Creek Rd. And Old Dixie Hwy.